Thursday, 22 March 2012

Lancet studies: Effect of daily aspirin on cancer

Lancet studies: Effect of daily aspirin on cancer: Source: Lancet, Lancet Oncology

There has been widespread media coverage on new evidence published by the Lancet in the form of three analyses investigating the association of daily aspirin consumption on cancer.
Effect of daily aspirin on risk of cancer metastasis
The first analysis investigated the frequency of distant metastasis in patients who developed incident cancer during randomised controlled trials of daily aspirin versus control.
This analysis included five large randomised trials (n=17,285) of daily aspirin (?75 mg daily) versus control for the prevention of vascular events. The trials included were restricted to UK trials because of the availability of centralised and well validated death certification and cancer registration. Electronic and paper records were reviewed for all patients with incident cancer. The effect of aspirin on risk of metastases at presentation or on subsequent follow-up (including post-trial follow-up of in-trial cancers) was stratified by ...

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