One class of antidepressants, selective serotonin reuptake inhibitors (SSRIs), targets serotonin, the ‘feel-good’ chemical that carries messages between nerve cells in the brain.
A SSRI side-effect is ‘blunting’, where patients say they cannot respond with the level of enjoyment they normally would. The Daily Mail
See also:
- Chronic escitalopram in healthy volunteers has specific effects on reinforcement sensitivity: a double-blind, placebo-controlled semi-randomised study (open access) Neuropsychopharmacology
- Scientists explain emotional ‘blunting’ caused by common antidepressants University of Cambridge
- Antidepressants can cause ‘emotional blunting’, study shows The Guardian
- Why antidepressants can blunt both negative and positive emotions New Scientist
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