Sepsis: the truth about this hidden killer

Sepsis: the truth about this hidden killer Sepsis is responsible for more deaths in the UK than bowel, breast and prostate cancer combined. So why is so little known about it?

At the end of May, the World Health Organization adopted a new resolution mandating all of its member states to have national action plans in place to tackle sepsis, a disease being called the “deadliest killer you’ve never heard of”. Even conservative estimates place the annual death toll at 6 million worldwide, a health burden equivalent to that of tobacco. In the UK alone, sepsis is responsible for 44,000 deaths every year, more than bowel, breast and prostate cancer combined. Despite this, a recent survey found that 44% of people in the UK have never heard of sepsis and have little idea that it is a life-threatening emergency.

So, what exactly is sepsis and why does it continue to slip through the net of our collective consciousness? The new international definition of sepsis describes it as a condition that arises when the body’s response to infection causes organ dysfunction. “There’s a range of ways in which this can happen,” says Prof Anthony Gordon, chair in anaesthesia and critical care at Imperial College London, and an National Institute for Health Research professor investigating sepsis. “The body’s immune response can be simply overwhelmed by the infection, or there’s a dysfunctional response producing too much inflammation. The body may already be immunosuppressed due to a trauma or fighting an initial infection, so the immune response is too weak.” Continue reading... The Guardian